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结肠根治术对结肠癌患者肠道菌群的影响 被引量:9

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摘要 目的观察结肠癌患者手术前后肠道菌群的变化情况。方法收集结肠癌患者手术前后粪便标本50例,利用实时荧光定量技术检测菌属细菌、梭杆菌属、梭菌属、双歧杆菌属和丁酸盐产生菌的数量及比例变化。结果拟杆菌属、梭杆菌属、梭菌属、双歧杆菌属和丁酸盐产生菌的拷贝数量均明显下降,这说明手术对于肠道菌群有抑制作用。从各类菌所占比例变化来看,拟杆菌属、梭菌属细菌的比例变化未发生明显改变,梭杆菌属类所占比例有所上升,而双歧杆菌和丁酸盐产生菌在菌群所占比例均有所下降。结论结肠癌手术对于患者肠道菌群的结构和功能都有着显著影响。
出处 《中国地方病防治》 CAS 北大核心 2016年第7期827-828,共2页 Chinese Journal of Control of Endemic Diseases
基金 长春市社会发展科技计划(12SF44)
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参考文献11

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