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肠道菌群与非酒精性脂肪性肝病 被引量:2

Gut microbiota and non-alcoholic fatty liver disease
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摘要 非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)在全球范围内越来越常见,造成极大的疾病负担,故对其发生、发展及防治措施进行研究变得十分迫切。近年来,肠道菌群被认为是机体的一个重要的"特殊器官",它参与机体的代谢并与相关疾病的发生、发展相关,与NAFLD的关系亦密切,值得深入探索,以期能寻找到防治NAFLD的新措施。 Non-alcoholic fatty liver disease (NAFLD) is getting more and more prevalent worldwide which causes great burden of disease, it is urgent to investigate the development, progression, prevention and treatment of NAFLD. Gut microbiota, as an "important and special organ" of the body, intimately participates in the metabolism of the body, the onset and progression of NAFLD as well, which merits further studies in order to find new breakthrough for NAFLD.
作者 周达 范建高 ZHOU Da FAN Jiangao(Department of Gastroenterology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, Chin)
出处 《上海医药》 CAS 2016年第19期13-16,共4页 Shanghai Medical & Pharmaceutical Journal
基金 "国家重点基础研究发展计划"项目(项目编号:2012CB517501) 国家自然科学基金项目(项目编号:81070322 81270491和81470840) 上海市科学技术委员会项目(项目编号:0914090350和10411956300) 中国肝炎防治基金项目(项目编号:XJS20120501) 上海市卫生局"百人计划"项目(项目编号:XBR2011007)
关键词 肠道菌群 非酒精性脂肪性肝病 发病机制 gut microbiota non-alcoholic fatty liver disease mechanisms
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