摘要
微RNA(miRNA)是在真核生物中新近发现的一个内源性小分子RNA家族,具有调控靶信使RNA(mRNA)转录、翻译、剪切靶mRNA并促进其降解的功能,被认为在机体发育过程中发挥重要作用,目前miRNA已成为肿瘤研究领域的热点。miRNA参与皮肤肿瘤的疾病进展,对miRNA的深入研究能增进对皮肤肿瘤发生、发展、转归等机制的认识,促进皮肤肿瘤诊断和治疗的快速发展。
MicroRNA （miRNA） is a newly discovered endogenous small messenger RNA （mRNA） tamily in eukaryotes,with the function of regulating mRNA transcription, translation, cutting target mRNA and promoting its degradation. It is thought to play an important role in the process of body development. Especially,it plays a significant role in the pathogenesis of tumor, studies have shown that miRNA is involved in the pathogenesis of melanoma progression. The intensive study of the miRNA undoubtedly can strengthen understanding of the occurrence ,development and prognosis of skin cancer, and promote the rapid development of the diagnosis and treatment.
出处
《医学综述》
2016年第19期3798-3801,共4页
Medical Recapitulate
基金
新疆维吾尔自治区国际科技合作计划项目(20146022)
