不同年龄组幕上脑实质室管膜瘤ADC值特点分析

Characteristics of ADC Values in Different Age Groups of Supratentorial Intraparenchymal Ependymoma

目的探讨不同年龄组幕上脑实质室管膜瘤ADC值特点及ADC值在幕上脑实质室管膜瘤诊断中的应用价值。方法搜集33例经手术和病理证实的幕上脑实质室管膜瘤患者影像资料,包括MRI平扫、扩散加权成像（DWI）及增强检查,将患者分为儿童组（〈12岁）、成人组（≥18岁）,对两组不同病理类型ADC值进行统计学分析和均值比较。结果儿童组12例,平均r ADC值0.94±0.52,WHOⅡ型4例,WHOⅡ～Ⅲ型1例,WHOⅢ型7例;成人组21例,平均r ADC值1.17±0.36,WHOⅡ型1例,WHOⅡ～Ⅲ型2例,WHOⅢ型18例;WHOⅡ型r ADC值儿童组小于成人组;WHOⅡ～Ⅲ型r ADC值儿童组小于成人组;WHOⅢ型儿童组r ADC值小于成人组,两组间r ADC值差异具有统计学意义（t=3.29,P=0.00）。结论儿童组、成人组幕上脑实质室管膜瘤影像表现不同,r ADC值存在差异,儿童组各病理类型r ADC值均小于成人组。ADC值在幕上脑实质室管膜瘤诊断中具有重要意义。

Objective To assess the characteristics of ADC values in different age groups of supratentorial intraparenchymal ependymomas（ SIEs）. Methods A retrospective analysis of 33 patients with SIE which were confirmed by surgery and pathology,all patients were examined by head MRI with contrast and DWI,Patients were divided into two groups according to age： children and adults. T test and Mean comparison were used to analyze the difference of r ADC values. Results Mean r ADC in the children group（ n = 12） is 0. 94 ± 0. 52,including 4 cases of WHOⅡ,1 case of WHOⅡ- Ⅲ,7cases of WHO Ⅲ; Mean r ADC in the adults group（ nn = 21） is 1. 17 ± 0. 36,including 1 case of WHOⅡ,2 cases of WHOⅡ- Ⅲ,18 cases of WHOⅢ. There were significant differences among the two groups（ WHOⅢ） in r ADC value（ t = 3. 29,P = 0. 00）. There were differences among the two groups（ WHO Ⅱ and Ⅱ- Ⅲ）. Conclusion There were MR and r ADC characteristics differences in the SIEs in different age groups. Children＇s group less than adult＇s group. ADC values can be applied as a complementary tool in the preoperative diagnosis of SIEs.