盐酸左氧氟沙星联合妇炎舒胶囊治疗盆腔炎的疗效观察

The curative effect of Levofloxacin hydrochloride combined with Fuyan shu capsule on patients with pelvic inflammatory disease

目的探讨盐酸左氧氟沙星联合妇炎舒胶囊治疗盆腔炎的疗效。方法选择我院收治的盆腔炎患者100例,随机分为观察组和对照组,各50例。对照组患者采用左氧氟沙星进行治疗,观察组患者采用左氧氟沙星与妇炎舒胶囊联合治疗,观察两组患者的治疗总有效率、治疗前后的细胞因子水平和不良反应发生情况。结果观察组总有效率为96.00%,高于对照组的76.00%(P<0.05);与治疗前对比,观察组治疗后IL-2和TNF-α水平明显降低,IL-10水平明显上升(P<0.05);与对照组对比,观察组治疗后IL-2和TNF-α水平明显更低,IL-10水平明显更高(P<0.05)。与对照组(30.00%)对比,观察组不良反应发生率(10.00%)明显更低(P<0.05)。结论盐酸左氧氟沙星联合妇炎舒胶囊治疗盆腔炎的疗效显著,有利于降低患者的炎症因子水平,提高患者的身体免疫力,减少不良反应的发生,值得临床应用及推广。

Objective To explore the curative effect of levofloxacin hydrochloride combining with Fuyan shu capsule on patients with pelvic inflammatory. Methods One hundred patients with pelvic inflammatory disease from June 2105 to June 2016 were randomly divided into observation group and control group, each group has 50 cases. The patients in control group were given levofloxacin antibiotic treatment, the patients in observation group were given levofloxacin combining with Fuyan shu capsule treatment, the efficient, cytokine levels and adverse reactions of two groups were observed. Results The rate of treatment efficient in the observation group was 96.00%, which was obviously higher than 76.00% in control group （P〈0.05）; compared with before treatment, the IL-2 and TNF-α level in observation group were significantly decreased, the IL-10 level was increased obviously （P〈0.05）; compared with the control group after treatment, the level of IL-2 and TNF-α was obviously decreased, the IL-10 level was obviously increased （P〈0.05）; the incidence of adverse reactions in control group was 30.00%, which was significantly lower than 10.00% in observation group （P〈0.05）. Conclusion The treatment of levofloxacin hydrochloride combining with Fuyan shu capsule in patiens with pelvic inflammatory shows definite curative effect, and can helpful to reduce the level of inflammatory factors, improve the body immunity, reduce the occurrence of adverse reactions, which is worthy of clinical wide application and promotion.