奥曲肽联合奥美拉唑治疗上消化道出血的疗效

Curative effect by octreotide combined with omeprazole in the treatment of upper gastrointestinal hemorrhage

目的探讨在上消化道出血中通过奥曲肽与奥美拉唑联合进行治疗的临床效果。方法 114例上消化道出血患者,根据住院顺序分为实验组和对照组,各57例。对照组患者给予奥美拉唑治疗,实验组患者在对照组基础上给予奥曲肽治疗。对比两组患者的止血情况以及再出血情况。结果实验组治疗总有效率98.25%高于对照组的85.96%,差异具有统计学意义(P<0.05)。实验组再出血率3.51%低于对照组15.79%,差异具有统计学意义(P<0.05)。结论在上消化道出血中通过奥曲肽与奥美拉唑联合进行治疗的临床效果显著,止血效果明显,并且再出血率比较低,值得在临床上推广。

Objective To investigate clinical effect by octreotide and omeprazole in combined treatment of upper gastrointestinal hemorrhage. Methods A total of 114 patients with upper gastrointestinal hemorrhage were divided by admission order into experimental group and control group, with 57 cases in each group. The control group received omeprazole for treatment, and the experimental group received additional octreotide. Comparison was made on hemostasis and rehemorrhage condition between the two groups. Results The experimental group had higher total effective rate as 98.25% than 85.96% in the control group, and the difference had statistical significance（P〈0.05）. The experimental group had lower rehemorrhage rate as 3.51% than 15.79% in the control group, and the difference had statistical significance（P〈0.05）. Conclusion Implement of octreotide and omeprazole in combined treatment of upper gastrointestinal hemorrhage shows precisely clinical effect, along with remarkable hemostasis effect and low rehemorrhage rate. This method is worth clinical promotion.