综合护理干预在非酒精性脂肪性肝病大学生患者中的应用

Application of comprehensive nursing intervention to college students with non-alcoholic fatty liver disease

目的探讨护理干预对大学生非酒精性脂肪性肝病(NAFLD)患者的实施和效果。方法选取40例大学生NAFLD患者,建立健康档案,饮食、运动和心理干预,健康追踪与教育,观察综合护理干预前后体质量指数(BMI)、丙氨酸转氨酶(ALT)、血清总胆固醇(TC)、三酰甘油(TG)和脂肪肝程度。结果干预后BMI、ALT、TC、TG指标均明显改善:BIM(24.60±1.93)kg·m-2,ALT(23.60±10.77)U·L-1,TC(4.24±0.84)mmol·L-1,TG(1.47±0.35)mmol·L-1,差异有统计学意义(P<0.05);干预前后脂肪肝病变程度构成差异有统计学意义(Z=-6.164,P<0.05)。结论综合护理干预能明显降低患者的BMI、ALT、TC、TG与肝脏影像学指标,促进疾病转归。

Objective To explore the effect of nursing intervention on non-alcoholic fatty liver disease（ NAFLD） college students.Methods Forty cases of college students with NAFLD were selected. Their health records were established and intervention was conducted on diet,exercise and psychological condition with health tracking and education. Body mass index（ BMI）,alanine aminotransferase（ ALT）,serum total cholesterol（ TC）,triglyceride（ TG） and fatty liver degree were observed before and after the comprehensive nursing intervention. Results BMI,ALT,TG,TC index were significantly improved after the intervention： BIM（ 24. 60 ± 1. 93） kg·m- 2,ALT（ 23. 60 ± 10. 77） U·L- 1,TC（ 4. 24 ± 0. 84） mmol·L- 1,TG（ 1. 47 ± 0. 35） mmol·L- 1. The difference was statistically significant（ P 〈 0. 05）. There was statistically significant difference in pathological changes in fatty liver before and after the intervention（ Z =- 6. 164,P 〈 0. 05）. Conclusions Comprehensive nursing intervention can significantly reduce the patients’ BMI,ALT,TC,TG and liver imaging indicators,and promote the prognosis of the disease.