丹参酮Ⅱa注射液对心肺复苏患者的疗效分析

Effect analysis of Sodium tanshinon Ⅱa silate on patients with cardiopulmonary resuscitation

目的观察丹参酮Ⅱa注射液在心源性猝死患者心肺复苏中的作用。方法将30例心源性猝死患者随机分成两组,在常规进行心肺复苏的基础上,治疗组给予丹参酮Ⅱa注射液,对照组为生理盐水。观察两组患者自主循环恢复时间;同时检测患者肌酸激酶同工酶(CK-MB)、肌钙蛋白I(CTNI)、血浆B型利钠肽(BNP)水平。结果丹参酮Ⅱa注射液治疗组患者恢复有效自主循环时间较对照组缩短(P<0.05);两组患者CK-MB、CTNI、BNP均上升,但治疗组的升高幅度低于对照组。结论丹参酮Ⅱa注射液增加了心肺复苏的成功率,减轻复苏后的心肌损伤和改善复苏后患者心功能。

Objective To observe the effect of Sodium tanshinon Ⅱa silate in cardiopulmonary resuscitation（ CPR） of sudden cardiac death（ SCD） patients. Methods Totally 30 SCD patients were divided into two groups at random,both based on conventional CPR,the treatment group received Sodium tanshinon Ⅱa silate injection,and control group was treated with saline. Observed two groups patients spontaneous circulation recovery time; At the same time detected creatine kinase（ CK-MB）,cardiac troponin I（ CTNI） and plasma B-type natriuretic peptide（ BNP）. Results Treatment group with Sodium tanshinon Ⅱa silate has shorter effective autonomous circulation time than the control group（ P〈0. 05）; The CK-MB,CTNI and BNP were both increased in two groups,but rate of increase in the treatment group was lower than that of the control group（ P〈0. 05）. Conclusion Sodium tanshinon Ⅱa silate increases the success rate of cardiopulmonary resuscitation,reduces myocardial injury and improves cardiac dysfunction after resuscitation.