利多卡因联合丙泊酚行无痛支气管镜检查的疗效和安全性探讨

Clinical efficacy and safety of lidocaine combined with propofol in painless bronchoscopy

目的探讨在利多卡因与丙泊酚联合麻醉下行无痛支气管镜检查的临床疗效及其安全性评估。方法排除对利多卡因或丙泊酚过敏患者[1],随机将84例行支气管镜检查患者分为实验组与对照组,各42例。联合使用利多卡因与丙泊酚的为实验组,单纯使用利多卡因的为对照组,比较两组四个时间点呼吸(RR)、氧饱和度(Sp O2)、收缩压(SBP)与心率(HR),满意度以及不良反应情况。结果实验组各时间点RR、Sp O2、SBP与HR水平均比对照组良好;苏醒后实验组不良反应更少,满意度更高。结论行无痛支气管镜检查时联合使用利多卡因与丙泊酚能取得不错的麻醉效果,能提高患者依从性与满意度。

Objective To evaluate the clinical efficacy and safety of painless bronchoscopy under combined anesthesia with lidocaine and propofol. Methods Totally 84 patients were randomly selected from 1 patients who had a history of mental illness,who had a history of mental illness,or who were allergic to lidocaine or propofol. The subjects were divided into experimental group and control group,42 cases in each group. Combined use of lidocaine and propofol as the experimental group,the simple use of lidocaine for control group,compared two groups of four time respiration（ RR）,oxygen saturation（ Sp O2）,systolic blood pressure（ SBP） and heart rate（ HR）,satisfaction,and adverse reaction conditions. Results Before anesthesia,two groups of patients with no obvious differences in each index. After anesthesia,the experimental group each time point Sp O2,SBP,RR and HR levels were better than those the control group; After recovery,the experimental group had less adverse reactions,higher satisfaction. Conclusion The combined use of lidocaine and propofol can achieve good anesthetic effect,and can improve patient compliance and satisfaction.