期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

抗3-羟基-3-甲基戊二酰辅酶A还原酶抗体实验室检测及临床意义 被引量：1

Laboratory tests and clinical significance of anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody
下载PDF
导出
摘要 抗3-羟基-3-甲基戊二酰辅酶A还原酶抗体是新近发现的一种自身抗体,与他汀类调脂药密切相关,可以作为免疫性坏死性肌病的免疫学标志物。本文拟就该抗体的发现、检测方法和临床意义进行简要综述。 Anti-3-hydroxy-3-methylglutaryl coenzyme A reductase（HMGCR） antibody is a newly recognized autoantibody,which is associated with the use of statins and is considered as an immunological marker of necrotizing autoimmune myopathy（NAM）.This article summarizes the discovery,laboratory tests and clinical significance of anti-HMGCR antibody.
作者 罗晶晶 高枫 闻洁曦 郝洪军 郭晶 黄一宁 LUO Jing-jing GAO Feng WEN Jie-xi HAO Hong-jun GUO Jing HUANG Yi-ning(Department of Neurology, Peking University First Hospital, Beijing 100034, China)
机构地区 北京大学第一医院神经内科
出处 《中国现代神经疾病杂志》 CAS 2016年第9期573-575,共3页 Chinese Journal of Contemporary Neurology and Neurosurgery
基金 2014年度北京大学第一医院青年科研基金资助项目~~
关键词 羟甲基戊二酰基CoA还原酶类 免疫测定 降血脂药 综述 Hydroxymethylglutaryl CoA reductases Immunoassay Antilipemic agents Review
分类号 R446.6 [医药卫生—诊断学]
  • 相关文献

参考文献13

  • 1Christopher-Stine L, Casciola-Rosen LA, Hong G, Chung T, Corse AM, Mammen AL. A novel autoantibody recognizing 200- kd and 100-kd proteins is associated with an immune-mediated necrotizing myopathy. Arthritis Rheum, 2010, 62:2757-2766.
  • 2Mammen AL, Chung T, Christopher-Stine L, Rosen P, Rosen A, Doering KR, Casciola- Rosen LA. Autoantibodies against 3- hydroxy-3-methylglutaryl-coenzyme A reductase in patients with statin-associated autoimmune myopathy. Arthritis Rheum, 2011, 63:713-721.
  • 3Mammen AL, Gaudet D, Brisson D, Christopher-Stine L, Lloyd TE, Leffell MS, Zachary AA. Increased frequency of DRBI*ll: Ol in anti - hydroxymethylglutaryl - coenzyme A reductase - associated autoimmune myopathy. Arthritis Care Res (Hoboken), 2012, 64:1233-1237.
  • 4Mammen AL, Pak K, Williams EK, Brisson D, Coresh J, Selvin E, Gaudet D. Rarity of anti - 3 - hydroxy - 3 - methylglutaryl - coenzyme A reductase antibodies in statin users, including those with self-limited musculoskeletal side effects. Arthritis Care Res (Hoboken), 2012, 64:269-272.
  • 5Drouot L, Allenbach Y, Jouen F, Charuel JL, Martinet J, Meyer A, Hinschberger O, Bader-Meunier B, Kone-Paut I, Campana- Salort E, Eymard B, Tournadre A, Musset L, Sibilia J, Marie I, Benveniste O, Boyer O; French Myositis Network [CN]. Exploring necrotizing autoimmune myopathies with a novel immunoassay for anti - 3 - hydroxy - 3 - methyl - glutaryl - CoA reductase autoantibodies. Arthritis Res Ther, 2014, 16:R39.
  • 6Musset L, Miyara M, Benveniste O, Charuel JL, Shikhman A, Boyer O, Fowler R, Mammen A, Phillips J, Mahler M. Analysis of autoantibodies to 3 - hydroxy - 3 - methylglutaryl - coenzyme A reductase using different technologies. J Immunol Res, 2014: ID405956.
  • 7Ge Y, Lu X, Peng Q, Shu X, Wang G. Clinical characteristics of anti - 3 - hydroxy - 3 - methylglutaryl coenzyme A reductase antibodies in Chinese patients with idiopathic inflammatory myopathies. PLoS One, 2015, 10:E0141616.
  • 8Dalakas MC. Inflammatory muscle diseases. N Engl J Med, 2015, 373:393-394.
  • 9Mammen AL, Tiniakou E. Intravenous immune globulin for statin-triggered autoimmune myopathy. N Engl J Med, 2015, 373:1680-1682.
  • 10Grable-Esposito P, Katzberg HD, Greenberg SA, Srinivasan J, Katz J, Amato AA. Immune- mediated necrotizing myopathy associated with statins. Muscle Nerve, 2010, 41:185-190.

同被引文献21

引证文献1

二级引证文献7

中国现代神经疾病杂志
2016年 第9期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部