摘要
手术是除泌乳素瘤外的垂体瘤的首选治疗方案，部分患者在术后可发生垂体功能减退，其中以急性肾上腺危象最为严重，而慢性肾上腺功能低下则不同程度的影响着患者的生活质量，因此术后对下丘脑.垂体.肾上腺（ HPA）轴进行准确的评估对垂体瘤术后患者的合理治疗显得至关重要，但目前尚缺乏对肾上腺轴进行评估的可靠方法。本文综述了肾上腺功能低下的危害、HPA轴评估方法的新进展以及术后糖皮质激素替代治疗的新观念，明确了术后重新评估和定期随访以及制定个体化方案的重要性。
Objective Surgical treatment is the first choice for treatment in pituitary adenomas except for prolactinomas.In part of patients after operation would occur hypopituitarism,which with acute adrenal crisis is the most serious, and chronic adrenal insufficiency is different degree affects the patient＇s quality of life.Therefore,it is very important to accurately assess the hypothalamic pituitary adrenal（ HPA） axis in patients with pituitary adenoma.But there is still a lack of reliable methods for evaluating adrenal axis.We reviewed the harm of adrenal insufficiency,HPA axis evaluation method of the new progress and postoperative glucocorticoid replacement treatment of new ideas, cleared the importance of reassessment and regular follow.up and the development of individual programs.
出处
《中国综合临床》
2016年第8期757-761,共5页
Clinical Medicine of China
