一例输血相关性GVHD

A Transfusion-Associated GVHD

报告1例12岁女性,患急性淋巴细胞性白血病第一次复发,在诱导化疗期全血细胞减少,输全血和颗粒细胞引起腹泻、皮疹,皮肤病理符合急性移植物抗宿主病改变。为此作者复习文献,对输血相关性GVHD的临床特点及防治措施作了介绍。

A case of the 12-year-old female patient with first relapsed acute lymphoblastic leukemia was reported. During the induction chemotherapy, the patient, transfused with whole blood and granulocytes, developed diarrhea and generalized macular rash. The skin biopsy showed some changes compatible with graft versushost disease (GVHD). Therefore, the related literature was reviewed, and the clinical features of transfusionassociated GVHD and the measures for its prevention and treatment were succinctly introduced.