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CA199、CA125及CEA联合检测诊断卵巢癌的临床价值 被引量:15

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摘要 目的研究糖类抗原199(CA199)、糖类抗原125(CA125)及癌胚抗原(CEA)联合检测诊断卵巢癌的临床价值。方法采用化学发光法检测64例卵巢癌(设为卵巢癌组)、79例卵巢良性肿瘤(设为卵巢良性肿瘤组)及80例健康妇女(设为正常对照组)的血清CA199、CA125及CEA表达水平,采用snk-q检验比较各组上述检测指标表达水平,并采用受试者工作曲线(ROC)方法计算各指标单一及联合检测卵巢癌的诊断效力。结果(1)三组CA199、CA125及CEA水平两两比较均有统计学差异(P均<0.05),且均为卵巢癌组>卵巢良性肿瘤组>正常对照组;(2)三种指标单一诊断时,CA125卵巢癌检出最高;(3)三种指标联合诊断时,≥1种阳性卵巢癌检出最高。结论卵巢癌患者CA199、CA125及CEA表达高于卵巢良性肿瘤和正常健康人群,三种联合检测有助于提高卵巢癌诊断能力。
出处 《贵州医药》 CAS 2016年第9期973-975,共3页 Guizhou Medical Journal
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参考文献11

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