急性胆系疾病心电图改变和肌钙蛋白升高的研究进展

Research progress in electrocardiogram changes and elevated troponin in blood during acute biliary diseases

急性胆系疾病是消化系统的常见病、多发病,可出现继发性心脏损伤的症状、体征、心电图及心肌酶改变等。心电图改变和肌钙蛋白升高是诊断急性心肌梗死的重要指标,但也可出现在其他急症如急性胆系疾病中。目前国内外关于急性胆系疾病引起心电图改变和血肌钙蛋白升高的研究不多,其机制也尚不明确,可能与迷走神经介导的神经反射,炎症作用及代谢紊乱等因素相关,且影响患者预后。该文章就急性胆系疾病心电图改变和血肌钙蛋白升高可能的机制及临床意义做一综述。

Acute biliary diseases are clinical common and frequent diseases. Some cardiovascular manifestations that secondary acute biliary diseases such as abnormalities in electrocardiography （ECG）, myocardial enzyme elevation can also be found during the disease progress. Although cardiac troponin elevation and ST-segment changes are often in- dicative of acute coronary syndrome , it has also been described in acute biliary diseases. The current mechanism about ECG changes and troponin elevation during acute biliary diseases may related with a vagally mediated reflex, infammation and metabolic disorders. The prognosis of the patients may be influneed by the elevated troponin. This article is a review on the clinical significance and possible mechanism of ECG changes and troponin elevation during acute biliary diseases.