热毒宁注射液联合拉氧头孢钠治疗小儿支气管肺炎的效果评价

Effect evaluation of Reduning injection combined with Latamoxef disodium in treatment of children with bronchial pneumonia

目的 探讨热毒宁注射液联合拉氧头孢钠治疗小儿支气管肺炎的效果。方法 选择2014年4月-2016年4月我院接诊的小儿支气管肺炎200例,按随机数字表法将其分为观察组和对照组,各100例。两组患儿均给予常规平喘、消炎、化痰治疗,对照组给予拉氧头孢钠治疗,观察组在对照组基础上加用热毒宁注射液。比较两组患儿临床症状、体征消失时间,临床疗效及不良反应。结果 观察组在发热、咳嗽、肺部啰音、胸部X线显示完全吸收时间上均较对照组短[（2.48±0.64）d vs（4.32±1.12）d,（2.84±0.83）d vs（4.20±1.07）d,（2.32±0.43）d vs（4.85±1.20）d,（4.02±0.52）d vs（6.87±1.47）d]（P〈0.01）;治疗后,观察组总有效率明显较对照组高（94.00%vs 82.00%）,两组比较差异有统计学意义（P〈0.01）;两组患儿治疗过程中均未发生明显不良反应。结论 热毒宁注射液联合拉氧头孢钠治疗小儿支气管肺炎效果显著,且用药安全性高,值得进行推广应用。

Objective To discuss the effect of Reduning injection combined with Latamoxef disodium in treatment of children with bronchial pneumonia.Methods 200 children with bronchial pneumonia from April 2014 to April 2016 in our hospital were researched.They were randomly divided into observation and control groups,with 100 cases in each group.Two groups were given conventional anti-inflammatory,asthma,phlegm treatment,the control group were treated with Latamoxef disodium,the observation group based on the control group were given Reduning injection.Clinical symptoms and signs disappeared time,clinical effect and adverse reactions of the two groups were compared.Results The time of fever, cough,pulmonary rales,chest X-ray showed complete absorption in observation group were shorter than those in the control group[（2.48±0.64）d vs （4.32±1.12）d,（2.84±0.83）d vs （4.20±1.07）d,（2.32±0.43）d vs （4.85±1.20）d, （4.02＋0.52）d vs （6.87±1.47）d]（P〈0.01）;after treatment,the total effective rate in the observation group was significantly higher than-that in the control group（94.00% vs 82.00%）,the difference was signifieant（P〈0.01）;there were no significant adverse reactions in the treatment of the two groups.Conclusion In children with bronchial pneumonia given Reduning injection combined with latamoxef sodium treatment of the reatment has effect significant,and the safety of medication is high,it＇s worthy of application and promotion.