体外反搏联合全视网膜激光光凝治疗非增生型糖尿病视网膜病变

Effects of external counterpulsation combined with laser photocoagulation for treatment of non-proliferative diabetic retinopathy

目的:探讨体外反搏联合全视网膜激光光凝治疗非增生型糖尿病视网膜病变的疗效。方法:采用前瞻性研究方法,选择2013-08/2016-02在我院诊治的非增生期糖尿病视网膜病变患者104例104眼作为研究对象,根据入院顺序分为观察组与对照组各52例52眼,对照组采用全视网膜激光光凝治疗,观察组在对照组治疗的基础上给予体外反搏治疗,观察两组预后情况。结果:观察组与对照组的总有效率分别为98.1%、84.6%,观察组明显高于对照组,差异有统计学意义(P<0.05)。观察组与对照组治疗后的患眼动脉EDV与PSV值都明显高于治疗前,差异有统计学意义(P<0.05),同时观察组治疗后的患眼动脉EDV与PSV值也明显高于对照组,差异有统计学意义(P<0.05)。观察组治疗前后的CMT值分别为198.13±45.32、200.46±31.94μm,而对照组分别为203.14±51.94、202.90±42.95μm,在组内与组间对比都无统计学意义(P>0.05)。结论:体外反搏联合全视网膜激光光凝治疗非增生型糖尿病视网膜病变具有很好的安全性,能促使眼动脉血流速度加快,从而提高治疗疗效。

AIM： To investigate the effects of external counterpulsation combined with laser photocoagulation for treatment of non-proliferative diabetic retinopathy. METHODS： A prospective study method were used from Aug. 2013 to Feb. 2016. A total of 104 cases in our hospital for treatment of non - proliferative stage of diabetic retinopathy patients were selected as the research object, and all the patients were equally divided into observation group and control group, 52 cases in each group according to the order of admission. Patients in control group were treated with panretinal laser photocoagulation treatment. The observation group were given external counterpulsation combined with laser photocoagulation for treatment, observed the prognosis in the two groups. RESULTS： The total efficiency in the observation group and the control group were 98. 1% and 84. 6%, the observation group was significantly higher than the control group （P〈0. 05）. The eye artery EDV and PSV values in the observation group and the control group after treatment were significantly higher than those before treatment （P〈0. 05）, while the observation group aftertreatment of eye artery EDV and PSV value were significantly higher than those in control group （P〈0. 05）. The CMT values in the observation group before and after treatment were 198. 13±45. 32μm and 200. 46±31. 94μm, while the control group were 203. 14±51. 94μm and 202. 90±42. 95μm that compared between the two groups were not statistically significant （P〉0. 05）. CONCLUSION： External counterpulsation combined with laser photocoagulation treatment has good safety in the treatment of non-proliferative diabetic retinopathy, it can promote eye artery blood flow speed, thereby improve the therapeutic effect.