开封地区年龄相关性白内障患者角膜球面像差分析

Analysis on corneal spherical aberration in patients with cataract in Kaifeng area

目的：调查开封地区年龄相关性白内障患者的角膜球差变化分布及与年龄的相关性。 方法：年龄相关性白内障患者427例466眼,年龄52-75岁,根据年龄段分为三组,术前使用Pentacam眼前节分析系统测量角膜前表面K值、角膜中央直径6 mm范围前表面球差、后表面球差和角膜总球差。 结果：所有患者平均角膜球差为0.339±0.153μm,50-60岁年龄组平均角膜球差为0.322±0.137μm,61-70岁年龄组平均角膜球差为0.326±0.157μm,71-80岁年龄组平均角膜球差为0.401±0.182μm。角膜K值与角膜总球差无相关性（r=0.034,P〉0.05）,角膜前表面球差、后表面球差及角膜总球差与年龄呈正相关（ r=0.253、0.327、0.233,均P〈0.01）。 结论：角膜球差随着人种的差别而有差异,开封地区老年人的角膜球差较白种人略高,且与年龄呈正相关。

AIM：To find out the mean corneal spherical aberration and its changes with age in Kaifeng population. METHODS： A total of 466 eyes of 427 Kaifeng subjects with cataract, whose age ranged from 52 to 75 years old, were divided into three groups according to the age. All the subjects were included in measuring K-readings of cornea, the corneal anterior and posterior surfaces of the spherical aberration and the total corneal spherical aberration using Pentacam（Oculus, Germany） at the 6-mm optical zone. RESULTS：The mean corneal spherical aberration（ CSA） of the whole groups was 0. 339±0. 153μm. Patients from 50 to 60 years old had CSA of 0. 322±0. 137μm, 0. 326±0.157μm was the CSA of the patients from 60 to 70 years old, while those from 70 to 80 years old have a CSA of 0.401 ± 0. 182μm. The corneal K - readings had no correlation with the total corneal spherical aberration （ r=0. 034, P〉0. 05）, anterior surfaces CSA, posterior surfaces and total CSA were positively correlated with age （ r =0.253, 0. 327, 0. 233, all P〈0. 01）. CONCLUSION：CSA is varied among the population and CSA of elderly in Kaifeng area are slightly higher than white people, and positively correlated with age.