右美托咪定在老年患者麻醉中的应用

The Application and Progress of Dexmedetomidine in Elderly Anesthesia

目的探讨右美托咪定在老年麻醉中的应用价值。方法需要手术治疗的老年患者,共计100例,随机、双盲原则分为观察组和对照组,每组50例。在全麻药物种类使用相同的情况下,对观察组加用右美托咪定进行麻醉维持,麻醉期间对两组患者的相关观察指标应用SPSS19.0软件,所获数据采用方差分析和t检验。结果两组患者麻醉药物用量存在差异,在自主呼吸开始时间、拔管时间、苏醒时间、血流动力学稳定、术中镇静程度以及苏醒之后的躁动等指标,观察组显著优于对照组(P<0.05),有显著性差异。结论老年患者在麻醉中采用右美托咪定可减少全麻药物的使用量,缩短患者的苏醒时间,降低患者的手术风险,提高治疗效果,在满足手术适应症和禁忌症的条件下值得临床推广应用。

Objective To investigate the application value and progress of dexmedetomidine in elderly anesthesia. Methods One hundred patients undergoing surgery from February of 2014 to February of 2015 were randomly divided into two groups（n=50） The study group received dexmedetomidine to maintain anesthesia, while the control group using the same kinds of general anesthetics. The relevant indicators of two groups were assessed. Results Due to the different dosage of general anesthetics, at the beginning of the spontaneous breathing time, extuhation time, wake up time, hemodynamic stability, introperative sedation and the agitation of wake, study group is better than that of control group.The differences were statistically significant（P〈0.05）. Conclusion Elderly patients during anesthesia using dexmedetomidine can decrease the amount of general anesthetics, reduce the awakening time of patients, cut down the risk of surgery patients, improve the effect of treatment. It＇ s worthy of clinical popular application under the condition of meet the surgical indications and contraindications.