参苓白术散加减治疗功能性消化不良脾虚气滞证疗效评价

Efficacy evaluation of ingredient-altered Shenling Baishu Powder in the treatment of functional dyspepsia or fullness of spleen-deficiency and qi-stagnation syndrome

目的探讨功能性消化不良脾虚气滞证患者采用参苓白术散加减治疗的疗效。方法选取2012年8月至2015年12月患有功能性消化不良的110例患者,以随机数字法将其分为两组,每组55例。对照组采用口服西药吗丁啉联合多酶生治疗,研究组采用中医参苓白术散进行治疗。比较两组患者治疗效果、治疗前后症状评分变化情况。结果研究组患者治疗总有效率为90.91%(50/55),明显高于对照组的76.36%(42/55);同时研究组患者治疗后各项临床症状评分均明显低于对照组,两组数据存在统计学意义(P<0.05)。结论利用参苓白术散加减治疗功能性消化不良临床效果突出,可以更好地改善患者的临床症状。

Objective To investigate the effect of ingredient-altered Shenling Baizhu Powder in the treatment of functional dyspepsia or fullness of spleen-deficiency and qi-stagnation syndrome. Methods One hundred and ten patients were selected in our hospital from August 2012 to December 2015 and randomly divided into two groups, with 55 cases in each group. The patients in control group received oral domperidone combined with enzyme therapy, while the patients in the observation group received Shenling Baishu Powder therapy. The efficacy, the changes of symptom scores before and after the treatment were recorded and compared. Results The total effective rate of the observation group was 90.91% （50/55）, which is significantly higher than 76.36% （42/55） of the control group, and the difference was statistically significant （P〈 0.05）. The changes of symptom scores in the observation group were also significantly lower than that of the control group, and the difference was statistically significant （P〈0.05）. Conclusion The efficacy of ingredient-altered Shenling Baishu Powder in the treatment of functional dyspepsia or fullness of spleen-deficiency and qi-stagnation syndrome is particularly prominent. It can improve the clinical syndrome.