SGB对血管性痴呆患者认知功能的疗效观察

Observation of curative effect by SGB for cognitive function in vascular dementia patients

目的观察星状神经节阻滞(SGB)对血管性痴呆(Va D)患者认知功能的临床效果。方法 76例Va D患者,随机分为治疗组(给予SGB治疗)和对照组(给予常规治疗),各38例,均连续应用4周,采用简易精神状态量表(MMSE)、Barthel指数分别对患者的认知能力、日常生活能力(ADL)进行评定。结果治疗前两组MMSE评分、ADL评分比较差异无统计学意义(P>0.05),治疗后治疗组MMSE评分(24.7±2.1)分、ADL评分(70.8±2.9)分优于对照组(20.3±1.5)、(63.7±3.5)分,差异有统计学意义(P<0.05)。结论 SGB有助于改善Va D患者认知功能障碍,提高患者生活活动能力。

Objective To observe clinical effect by stellate ganglion block（SGB） for cognitive function in vascular dementia（Va D） patients. Methods A total of 76 Va D patients were randomly divided into treatment group（received SGB treatment） and control group（received conventional therapy）, with 38 cases in each group. Their treatment all lasted for 4 weeks. Cognitive ability and activity of daily living（ADL） of patients were evaluated by mini-mental state examination（MMSE） and Barthel index. Results There was no statistically significant difference of MMSE and ADL scores between the two groups before treatment（P〉0.05）. After treatment, the treatment group had all better MMSE score as（24.7±2.1） points and ADL score as（70.8±2.9） points than（20.3±1.5） and（63.7±3.5） points in the control group. Their difference had statistical significance（P〈0.05）. Conclusion SGB is helpful for improving cognition impairment and ability of daily living in Va D patients.