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钙化性主动脉瓣疾病合并升主动脉扩张的危险因素分析

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摘要 目的分析钙化性主动脉瓣疾病(CAVD)合并升主动脉扩张的危险因素。方法选取CAVD行外科手术患者527例,根据升主动脉内径分为扩张组72例和非扩张组255例。比较两组患者的临床资料、超声数据及血清生物学检测结果,对有统计学意义的指标进行二分类Logistic分析。结果两组BMI、高血压、脉压指数(PPI)、出现症状至治疗时间、主动脉瓣反流面积、左心室重构指数(LVRI)、LDL、脂蛋白a、同型半胱氨酸、中性粒细胞与淋巴细胞比值比较,P均〈0.05。多因素Logistic回归分析显示,PPI(OR=1.127,95%CI为1.151-1.884)、LVRI(OR=1.189,95%CI为1.147—1.653)、脂蛋白a(OR=1.323,95%CI为1.156-1.401)与升主动脉内径扩张有关(P均〈0.05)。结论PPI、LVRI、脂蛋白a是CAVD患者升主动脉扩张的独立危险因素。
出处 《山东医药》 CAS 北大核心 2016年第38期42-44,共3页 Shandong Medical Journal
基金 河南省重点科技攻关资助项目(142102310510)
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