中药封包与双氯芬酸钠对膝关节骨性关节炎临床疗效对比分析

Comparison of Clinical Curative Effect Between Traditional Chinese Medicine Packet and Diclofenac Sodium on Knee Osteoarthritis

目的:对比中药封包与双氯芬酸钠治疗膝关节骨性关节炎(KOA)的临床疗效。方法:将我院2015年1月至2015年7月收治的88例KOA患者根据随机数字表分为治疗组和对照组。治疗组采用中药封包治疗,对照组采用双氯芬酸钠常规治疗,2组根据《中药新药临床研究指导原则》及西安大略大学和麦克马斯特大学骨关节炎指数(WOMAC)标准进行判定,并对比2组治疗疗效。结果:2组患者在接受治疗后,病情均有所缓解。治疗组临床控制5例,显效24例,有效13例,无效2例,总有效率95.45%;对照组临床控制2例,显效11例,有效24例,无效7例,总有效率84.09%。2组患者的WOMAC评分均显著低于治疗前,且治疗组的临床效果更为显著,差异有统计学意义(P<0.05)。结论:给予KOA患者采用中药封包治疗,疗效良好,值得临床推广。

Objective：To compare the clinical curative effect of traditional Chinese medicine packet and diclofenac sodium treatment on knee osteoarthritis （KOA） . Methods：A total of 88 patients with KOA according to random number table were randomly divided into treatment group and control group. Treatment group was treated with traditional Chinese medicine packet,the control group recened diclofenac sodium conventional treatment. Traditional Chinese medicine new medicine clinical research guiding principles and Womac standard was used to identify treatment efficacy. Results：Two groups of patients after treatment, the illness were eased. Treatment group clinical control in 5 cases,24 cases were markedly effective,effective 13 cases,2 had no effect,the total effective rate was 95.45%. Control group clinical control in 2 cases, 11 cases were markedly effective, effective 24 cases, 7 had no effect, the total effective rate was 84.09%. WOMAC scores in both groups were significantly lower than that before the treatment, and the curative effect of treatment group was more significant （P〈0.05） . Conclusion：KOA patients treated with traditional Chinese medicine packet has good curative effect is worthy of clinical promotion.