IgA肾病的治疗进展

Research Progress in Management of IgA Nephropathy

IgA肾病(IgAN)是肾小球疾病最常见的病理类型,也是引起终末期肾病最常见的病因,因此寻找有效的治疗方法来阻止肾功能进展是有必要的,传统治疗上以控制血压、血管紧张素转换酶抑制剂、血管紧张素受体拮抗剂、糖皮质激素、免疫抑制剂等为主,近年来随着对IgAN发病机制等方面了解的深入,新的治疗方案不断被提出。

Immunoglobulin A nephropathy （IgAN） is the most common type of glomerulonephritis in the world and causes end-stage renal disease （ESRD）, So there is a need for effective treatment strategies to prevent the decline in kidney function. Traditional treatment is based on blood pressure control, angiotensin converting enzyme inhibitors （ACEI） or angiotensin receptor blockers （ARB）, corticosteroid and immunosuppressive. In recent years, along with a better understangding of its pathogenesis, the new treatment has been put forward.