SWI联合DWI在新生儿颅内出血疾病中的应用价值

The application value of susceptibility weighted imaging combined with diffusion weighted imaging in the diagnosis of neonatal intracranial hemorrhage

目的:探讨联合磁敏感加权成像(SWI)及扩散加权成像(DWI)扫描技术在新生儿颅内出血疾病中的应用价值。方法:对58例经临床诊断为颅内出血的新生儿行头部MRI检查,包括常规MRI(T1WI、T2WI、T2Flair)及功能成像SWI和DWI,比较各序列影像学征象并对结果进行统计分析。结果:本组58例新生儿中,常规MRI扫描检出颅内出血为27例,而SWI序列发现38例;T1WI、T2WI及T2Flair发现出血灶数量分别为56、45和24个,SWI检出的颅内出血灶共147个,明显多于常规序列,两者比较有统计学意义。结论:SWI对颅内出血病灶检出率较常规MRI有明显优势,而DWI对颅内早期脑白质损伤病灶方面更为敏感。常规MRI扫描联合应用SWI及DWI功能成像扫描技术更有助于提高新生儿脑出血或脑出血并局灶性脑白质损伤的诊断准确率,并有利于对治疗进行指导以及评估预后。

Objective： To study the value of susceptibility weighted imaging（SWI） in combination with the diffusion weighted imaging（DWI） in the diagnosis of neonatal intracranial hemorrhage. Methods： A study was conducted including 58 neonates who were suspected neonatal intracranial hemorrhage. All MR examinations were performed at 1.5 Tesla unit including conventional MR（TIWI, T2WI, T2 Flair）, SWI and DWI. The imaging features of various sequences were compared, and the results were statistically analyzed. Results： Among 58 neonates with intracranial hemorrhage, 38 cases were confirmed by SWI, only 27 cases were found by conventional MR sequences. Altogether 147 hemorrhagic lesions were detected by SWI, while only 56, 45 and 24 lesions were found by TIWI, T2WI and T2 Flair. Conclusion： SWI sequence has more sensitivity than conventional sequences in detecting the intracranial hemorrhage of neonate. While DWI has more predominant advantage in punctate white matter lesions（PWML）. Conventional MRI combined with SWI and DWI functional imaging scanning technologyis more helpful to improve the diagnostic accuracy of the neonatal cerebral hemorrhage or cerebral hemorrhage with PWML, and it is helpful to guide the treatment and evaluate the prognosis.