EB病毒血清抗体水平与鼻咽癌临床分期相关性研究进展

Research progress on the relationship between the level of EBV antibodies and the tumor stages of nasopharyngeal carcinoma

鼻咽癌是高发于东南亚地区和中国南方的恶性肿瘤,其发病与EB病毒(Epstein-Barr virus,EBV)感染关系密切,EBV与鼻咽癌关系的研究近些年备受关注。但以往研究多倾向于EBV抗体与鼻咽癌筛查、诊断的关系,而EBV抗体水平与鼻咽癌分期的关系研究尚不多且争议较大。本文就近年EBV抗体水平与鼻咽癌临床分期关系的研究进行综述。

Nasopharyngeal carcinoma （NPC） is prevalent in Southeast Asia, especially in the area of southern China. It is acknowl-edged that NPC is absolutely related to EBV infection. Nevertheless, there are just a few researches about the relationship between the level of EBV antibodies and the tumor stages and it hasn＇t come to conclusion. This review makes a summary on present research progress and would be valuable for the better understanding of the contribution of EBV antibodies to the tumor stages in NPC.