切口感染51例合理用药分析

Analysis of rational drug use in 51 cases of incision infection

目的:探讨我院剖宫产手术后切口感染病例的用药合理性。方法:调取2013年9月—2015年8月剖宫产手术切口感染病例(剔除掉脂肪液化病例,分析血培养阳性的感染病例),逐一分析抗菌药物预防性应用的合理性。结果:2013年9月至2015年8月51例切口感染病例中,断脐后给药37例,其中20例有高危因素,仅15例进行了追加抗感染,但给药间隔时间长,24 h内用药频次不够,51例手术5例合用了替硝唑。结论:切口感染病例中不合理用药情况较为普遍,应加强抗菌药物的培训,做到个体化给药。

OBJECTIVE To investigate rationality of drug use in patients with incision infection after cesarean section in our hospital.METHODS Rationality of prophylactic antimicrobial agents was analyzed in patients with incision infection after cesarean section（patients with fat liquefaction were excluded,infection patients with positive blood culture were analyzed）from September 2013 to August 2015.RESULTS Of 51 patients with incision infection from September 2013 to August 2015,37 received drugs after dissection of umbilical cord,20 of them had high risk factors,only 15 had additional drugs against infection,with too long interval of medication,insufficient medication frequency within 24 h.Of 51 patients,5 patients concurrently received tinidazole.CONCLUSION Irrational drug use is relatively common in patients with incision infection,so training on antimicrobial agents should be enhanced to realize individualized medication.