血管疾病精准医学研究模式的现状与展望

Current status and future perspectives of precision medicine research model in vascular disease

精准医学是医学研究未来的方向,其目的在于将现有的基因组学研究进行规范、整合、共享,加速医学研究进程,提高医学研究效率,让基因组学研究的成果更快更好的服务于临床。本文回顾了腹主动脉瘤、静脉血栓栓塞症的疾病基因组学研究,氯吡格雷、华法林的药物基因组学研究的部分研究成果。精准医学已在血管疾病的筛查、诊断、药物治疗等方面有了初步的应用。各血管疾病诊疗中心共同努力,建立我国血管疾病的精准医学研究模式是未来的发展方向。

Precision medicine is the future direction of medical research. The purpose of promoting precision medicine is standardizing,integrating and sharing present achievements of genomics,accelerating the progress and improving the efficiency of medical research,and transferring the achievements of genomics on clinical application faster and better. This paper reviews the achievements of genomics on abdominal aortic aneurysm,venous thromboembolism disease,and the achievements of pharmacogenomics on warfarin and clopidogrel. The preliminary applications of precision medicine on vascular disease have already started. Establishing the precision medicine research model on vascular disease is the future direction.