2009—2012年某院耐亚胺培南鲍曼不动杆菌感染危险因素

Risk Factors of Nosocomial Imipenem- resistance Acinetobacter Baumannii Infection during 2009- 2012

目的分析感染耐亚胺培南鲍曼不动杆菌的危险因素,为临床防治鲍曼不动杆菌感染提供参考。方法采用病例-对照研究方法回顾性调查2009—2012年鲍曼不动杆菌感染病例,进行单因素和多因素Logistic回归分析危险因素。结果医院耐亚胺培南鲍曼不动杆菌感染的危险因素,经单因素分析结果显示,高龄、住院时间长、使用抗生素超过3种、广谱抗菌药使用时间超过7 d、侵入性操作等因素;多因素分析结果显示,主要有住院时间长、静脉导管、导尿、癌症、广谱抗菌药使用时间超过7 d和抗生素使用超过3种。结论发现鲍曼不动杆菌感染的危险因素,对加强防治鲍曼不动杆菌感染具有重要意义。

Objective To analyze risk factors of imipenem- resistance Acinetobacter baumannii nosocomial（ IRAB） infection,which provides a reference for preventing and curing IRAB. Methods IRAB infection cases were retrospectively investigated and logistic regression was used to analyze the risk factors. Results According to the single factor analysis,old age,history of invasive procedures,more than 3 kinds of antibiotics used,broad- spectrum antibiotics used more than 7 d performed were related to nosocomial IRAB infection. Multiple factors analysis showed that the risk factors of nosocomial IRAB infection were long stay in hospital,catheterization,more than 3 kinds of antibiotics used,cancer,broad- spectrum antibiotics used more than 7 d,canal of Arantius. Conclusion Analysis of risk factors highly related to infection by IRAB has great significance in its prevention and treatment.