摘要
目的分析1992—2015年许昌市新生儿乙型病毒性肝炎(乙肝)疫苗接种成本效益,为乙肝的预防和控制策略提供经济学依据。方法运用成本效益分析方法,对许昌市新生儿乙肝疫苗接种总成本、成本效果、成本效益和成本效用进行测算及分析。结果许昌市对新生儿乙肝疫苗免疫接种投入成本2 263.84万元,获得总经济效益138.29亿元,净效益138.06亿元,效益成本比为601.26∶1。共减少乙肝病毒表面抗原阳性携带者114 320例,慢性乙肝11 432例,肝硬化1 143例,肝癌114例,成本效果比为196.84∶1。共挽回65 992.97个失能调整寿命年(DALY),成本效用比为345.06∶1。结论许昌市实施新生儿乙肝疫苗预防接种的经济效益和社会效益非常显著。
Objective The cost-benefit analysis was carried out in hepatitis B vaccine inoculation for infants from 1992 to 2015 in Xuchang City, to provide an econamic base for the further improvement of hepatitis B immunization strategy. Methods It was caculated on total cost, cost-effectiveness, cost-effectiveness and cost-effectiveness of the vaccination that a suitable analysis was performed in benefitial to infants for hepatitis B vaccine immunization. Results The total benefit was 13. 829 billion yuan, and the net benefit 13. 806 billion yuan and a cost for hepatitis B vaccine inoculation 22. 638 4 million yuan, with a benefit/cost ratio of 601. 26 ∶ 1. There were 114 320 cases of HBsAg positive, 11 432 cases with chronic hepatitis B, 1 143 cases related liver cirrhosis and 114 cases with liver cancer reduced, with a cost-effectiveness ratio of 196. 84 ∶ 1. A total of 65 992. 97 DALY was restored, and cost-utility ratio was 345. 06 ∶ 1. Conclusion The social and economic effect was very significant by implementation of infants inoculation of hepatitis B vaccine in Xuchang City.
出处
《微生物学免疫学进展》
2016年第5期47-50,共4页
Progress In Microbiology and Immunology
关键词
新生儿
乙肝疫苗
成本
效益
Infant
Hepatitis B vaccine
Cost
Benefit
