肛周脓肿合并糖尿病的脓液培养和药敏分析

Pus Culture of the Patients with Perianal Abscess Complicated with Diabetes,and its Drug-sensitivity Test Analysis

为探讨肛周脓肿合并糖尿病者脓液菌群分布特点及耐药性，回顾2010年1月至2014年1月收治的肛周脓肿患者资料，其中合并糖尿病者75例（观察组），未合并糖尿病者78例（对照组），对比分析2组患者脓液细菌培养及药敏试验结果。结果显示，观察组脓液中克雷伯菌属检出率明显高于对照组，P〈0．05；其他菌种分布比较差异无统计学意义，P〉0．05。肛周脓肿病原菌对大多数常用抗菌药物的耐药性均较高，敏感性较低。革兰阳性菌对万古霉素敏感性最高，达100％；革兰阴性菌对亚胺培南敏感性最高，达98．9％。结果表明，合并糖尿病的肛周脓肿患者克雷伯菌分布较高，临床中应选择有针对性的抗生素治疗。

In order to investigate the flora distribution features and its drug-resistance of the pus from the patients of perianal abscess complicated with diabetes,authors retrospectively analyzed the data of 153 cases of perianal abscess admitted in author＇s department from Jan. 2010 to Jan. 2014 yr. among them 75 complicated with diabetes （as observation group） , rest 78 without diabetes （as control group） ;then compared and analyzed both group＇s bacterial culture of pus and its drug-sensitivity test results.As results,the detected rate of Klebsiclla of observation group was significantly higher than that of control group（ P 〈0.05） ,while other bacterial species distribution had no statistical difference between two groups（ P 〉0. 05） ;the pathogens of perianal abscess had higher drug-resistance and lower sensitivity on most common antibacterial drugs,G＋ bacteria＇s sensitivity on vancomycin belongs to the first （up to 100%）,while G bacteria＇s sensitivity on imipenem belongs to the first （up to 98.9%）.Results show that in the patients of perianal abscess complicated with diabetes the distribution of Klebsiella is predominant,therefore it should choosing the customized antibiotics to treat this disease clinically.