自制保健药酒抗疲劳相关功效的实验研究

Pharmacological Study on Anti-fatigue Effect of Health Wine

目的：观察针对亚健康人群而配制的保健药酒的抗疲劳相关功效。方法：将小鼠随机分成4组,分别为空白对照组、白酒对照组及保健药酒低、高2个剂量组,连续给药25~30 d后观察药酒对小鼠负重游泳时间、运动后尿素氮增长、肝糖原及血清乳酸含量的影响。结果：保健药酒能增强小鼠运动耐力,增加肝糖原蓄积,抵抗剧烈运动中产生的乳酸含量的增加,并加快乳酸的消除。结论：保健药酒具有基本的抗疲劳作用。

Objective： To investigate the anti- fatigue effect of a health wine that prepared for sub- heath people. Methods： Mice were randomly divided into four groups,the blank group,white wine control group,low and high dose health wine groups（ 1 m L·kg- 1,2 m L·kg- 1）,mice were given corresponding wine or saline for 25 ~ 30 days,then recording the loaded swimming time of mice,determining the serum BUN,hepatic glycogen and serum lactic acid contents. Results： Health wine could enhance the endurance,increase glycogen accumulation,resistance to the increasing of lactic acid produced in the intense exercise and accelerate the elimination of lactic acid. Conclusion： Health wine has a basic anti- fatigue effect.