中西医结合治疗急性胰腺炎有效率Meta分析

Combination of Chinese and western medicine treatment of acute pancreatitis effective rate: meta-analysis

目的系统分析中西医结合治疗急性胰腺炎的临床有效率,并作出客观真实的评价,指导临床中西医结合的合理治疗。方法通过检索CNKI、万方、维普3个数据库,根据严格的纳入和排除标准进行文献检索和筛选,并使用Jadad量表进一步对纳入文献进行评估,通过使用Stata SE 12软件进行定量的系统分析。结果本研究共38篇随机对照文献符合纳入标准,患者共计2 892例。Meta分析结果显示,中西医结合治疗急性胰腺炎较常规西药治疗临床有效率合并效应量OR=4.03,其95%可信区间为(3.17,5.12);合并效应量检验Z=11.38,P<0.01,两组间比较,差异有统计学意义(P<0.01)。结论中西医结合治疗急性胰腺炎可以明显改善临床有效率。

Objective To explore systematic analysis of combination of traditional Chinese and western medicine in the treatment of acute pancreatitis（ AP） effective rate,make an objective evaluation and to guide clinical rational treatment of combination of Chinese and western medicine. Methods The literatures about Chinese and western medicine treatments for AP were retrieved from CNKI,Wanfang Data Knowledge Service Platform and Chinese sci-tech periodical full-text database（ CQVIP）. The literatures which were retrieved and screened according to strict inclusion and exclusion criteria,furthermore,Jadad scale was used to access the randomly controlled trials. To analyze the efficacy of integrative treatment of AP by the using Stata SE 12 software,quantificationally and systematically. Results There were final 38 randomly controlled literatures met the inclusion criteria,including 2 892 patients. According to the results of the meta-analysis： integrated traditional Chinese and western medicine treatment of AP overall clinical efficacy was more efficient than the conventional western medicine,the the combined effect value OR = 4. 03,the 95% CI（ 3. 17,5. 12）,the test of the combined effect（ test for Overall Effect）,Z = 11. 38,comparison between the two groups,the difference was statistically significant（ P〈 0. 01）. Conclusion Integrated traditional Chinese and western medicine can significantly improve the treatment of acute pancreatitis clinical effective rate.