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精子DNA碎片率与体外受精结局的相关性研究 被引量:7

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摘要 目的:分析精子DNA碎片与体外受精(IVF)结局的相关性。方法:选取东莞市第三人民医院2014至2015年收治的男性患者200例作为研究对象,采用染色质扩散试验的方法进行精子DNA碎片与体外受精的检测,将精子中的DNA碎片率(DFI)、精液基本数据、受精率、可移植胚胎率进行分析,对精子DNA碎片率(DFI)、精子分析得出的各项参数进行回归分析。结果:经分析发现,精子DFI和精子活动率呈现负相关,采用密度梯度法对前期和后期的精子DFI进行分析,发现前后精子DFI和精子DNA碎片与IVF结局的受精率呈现负相关,差异具有统计学意义(P<0.05)。结论:精子DFI能够直接影响精子的活力和精子DNA碎片与IVF结局的受精率,其指标检测能够有效预测精子DNA碎片与IVF结局的受精率。
作者 蔡昭炜
出处 《深圳中西医结合杂志》 2016年第17期15-16,共2页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
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