米非司酮预处理在腹腔镜子宫肌瘤剔除术中的应用价值

The Clinical Value of Mifepristone Pretreatment in Laparoscopic Surgery of Uterine Fibroids

目的:研究腹腔镜下子宫肌瘤剔除术前应用米非司酮预处理的临床价值。方法:选取77例子宫肌瘤患者按随机数字奇偶法分为对照组(38例)和观察组(39例)。对照组行常规腹腔镜子宫肌瘤剔除术,观察组于术前用米非司酮进行处理。比较两组患者术前后情况。结果:两组患者术前子宫肌瘤直径比较,差异无统计学意义(P>0.05);观察组预处理后子宫肌瘤直径与之前比较,差异具有统计学意义(P<0.05);对照组手术时间、术中输血率、术中出血量均显著高于观察组(P<0.05),两组患者的术后住院时间与血红蛋白比较,差异均无统计学意义(P>0.05)。结论:米非司酮预处理在腹腔镜子宫肌瘤剔除术中可明显缩小子宫肌瘤体积,减少术中出血量,降低术中输血率,缩短手术时间。

Objective To find laparoscopic myomectomy preoperative mifepristone pretreatment clinical value. Methods 77 patients with uterine fibroids oriented sub study were randomly divided into parity law control group （38 cases） and observation group （39 cases）. The control group underwent conventional laparoscopic myomectomy, the observation group in the preoperative treatment with mifepristone. Comparison of the two groups of patients before and after surgery cases. Results The results showed no significant difference （P 〉 0.05） before the two groups of patients Uterine fibroids diameter; observation group after pretreatment uterine fibroids diameter before comparison （P 〈 0.05）; the control group operative time, intraoperative blood transfusion rate, intraoperative bleeding were significantly higher than those in the observation group （P 〈 0.05）, postoperative hospital stay between the two groups no significant difference （p hemoglobin〉 0.05）. Conclusion Mifepristone pretreatment laparoscopic myomectomy can be significantly reduced fibroid volume, reduce blood loss, lower blood transfusion rate, shorten the operation time.