一类连续生物过程的双目标优化

Bi-objective optimization for a class of continuous bioprocess

研究了甘油连续生物歧化过程的双目标优化.针对甘油生物歧化为1,3-丙二醇过程的还原途径酶催化非线性动力系统,首先构造了使甘油转化为1,3-丙二醇的转化率和3-羟基丙醛的浓度同时达到最优的双目标优化模型,其次利用加权和方法对其进行求解,最后获得了双目标优化问题的Pareto最优解集及Pareto最优前沿.

Bi-objective optimization of continuous bio -dissimilation process of glycerol is studied .Accord-ing to a nonlinear dynamic system of enzyme -catalytic kinetics on the bioprocess , a bi-objective optimization model that can simultaneously optimize the conversion rate of glycerol bioconversion to 1 ,3-propanediol and the 3-hydroxypropionaldehyde concentration is first established .Secondly , the bi-objective optimization problem can be solved by using the weighted -sum method .Thirdly , the Pareto optimal solution set and the Pareto -opti-mal front for bi-objective optimization problem are obtained .