急性缺血性卒中患者合并脑微出血的相关因素分析

The research on related factors about the ischemic stroke with cerebral microbleeds

目的探讨急性缺血性卒中患者发生脑微出血(CMBs)的危险因素。方法应用磁敏感加权成像技术检测CMBs,按照是否并发脑微出血分为CMBs组54例和无CMBs组44例,分析对比2组的一般资料和生化检查,分析患者发生CMBs的相关危险因素。结果与无CMBs组比,CMBs组的胆固醇水平明显偏低,同型半胱氨酸明显升高,年龄、高血压病史比例显著偏高,差异有统计学意义(P<0.05)。结论急性缺血性卒中患者中,脑微出血的发生与年龄、高血压、抗血小板药物应用、胆固醇、同型半胱氨酸具有相关性。

Objective To explore the risk factors of cerebral microbleeds （CMBs） occurred in patients with acute ischemic stroke. Methods Apply Susceptibility-weighted Imaging to detect CMBs, According to the results of SWI , the patients were divided into CMBs group （n= 54） and non-CMBs group （n= 44） .General clinical data and biochemical variables were compared between two groups. Results The total cholesterol level was significantly lower while the plasma homocysteine level was significantly higher in CMBs group than in non-CMBs group .Age, the proportion of high blood pressure and ant platelet durg application were significantly higher in CMBs group than in non-CMBs group （P〈0.05）. Conclusion In patients with acute ischemic stroke, CMBs was significantly associated with age, high blood pressure, ant platelet drug application, cholesterol, homocysteine.