经筋排刺电针对中风后肩痛患者血清IL-6、TNF-α、NO水平及疗效的影响

Effect of Muscle-region Alignment Electroacupuncture in Treating Post-stroke Shoulder Pain and on the Levels of Serum IL-6,TNF-α,and NO

目的观察经筋排刺电针治疗中风后肩痛的疗效及作用机制。方法将80例患者随机分为经筋排刺组和常规针刺组,主要观察治疗前后简明麦吉尔疼痛量表评分和血清IL-6、TNF-α及NO水平。结果经筋排刺电针治疗和常规针刺治疗中风后肩痛,在简明麦吉尔疼痛量表评分和血清IL-6、TNF-α、NO水平较治疗前明显降低,而经筋排刺电针治疗较常规针刺治疗下降的水平更加显著。结论经筋排刺电针治疗中风后肩痛的作用机制可能是降低血清IL-6、TNF-α、NO水平,减少或抑制了炎性因子的释放,抑制了炎性反应,从而改善症状。

Objective To observe the therapeutic efficacy and action mechanism of muscle-region alignment electroacupuncture in treating post-stroke shoulder pain. Method Eighty patients were randomized into a muscle-region alignment needling group and a conventional acupuncture group. The Short-form McGill Pain Questionnaire （SF-MPQ）, and serum levels of IL-6, TNF-α, and NO were majorly observed before and after the treatment. Result The muscle-region alignment electroacupuncture and conventional acupuncture both obviously reduced the SF-MPQ score and down-regulated the serum levels of IL-6, TNF-α, and NO, and the decreases by the muscle-region alignment electroacupuncture were more significant than that by the conventional acupuncture. Conclusion The action of muscle-region alignment electroacupuncture in treating post-stroke shoulder pain is plausibly by down-regulating serum levels of IL-6, TNF-α, and NO, reducing or inhibiting the production of inflammatory factors and restraining inflammation.