新疆691例维吾尔、汉族结肠息肉患者临床分析

Comparison of 691 cases of colonic polyps in Uyghur and Han of Xinjiang

目的了解新疆维吾尔族与汉族人群中结肠息肉的临床特点及发病规律。方法在新疆医科大学第一附属医院住院并经结肠镜检查确诊结肠息肉患者691例为研究对象,维吾尔族106例,汉族585例,使用SPSS16.0 for windows软件进行统计分析。结果单发息肉占43.42%,多发息肉占56.58%;管状腺瘤占65.70%,绒毛状-管状腺瘤占5.21%,增生性息肉占7.09%,炎性息肉占23.30%;乙状结肠息肉占45.15%,降结肠息肉占38.35%,横结肠息肉占31.26%,升结肠息肉占22.29%。维吾尔族患者发病年龄早于汉族患者,差异有统计学意义(P<0.01)。维吾尔族患者的高密度脂蛋白胆固醇(HDL-C)低于汉族患者,差异有统计学意义(P<0.05)。维吾尔、汉族患者在性别、饮酒史、吸烟史、临床症状、分布部位、空腹血糖、甘油三酯(TG)、总胆固醇(TC)、LDL-C及血清钾、钠、钙等差异无统计学意义(P>0.05)。结论维吾尔族结肠息肉患者发病年龄早于汉族结肠息肉患者。维吾尔族结肠息肉患者HDL-C水平低于汉族结肠息肉患者。多发息肉多见于汉族老年结肠息肉患者。

Objective To investigate the clinical characteristics and pathogenesis of colonic polyps in Uyghur and Han populations in Xinjiang. Methods 691 cases of Uyghur and Han which were diagnosed as colonic polyps by colonoscopy in the First Affiliated Hospital of Xinjiang Medical University hospital were statistical analyzed by SPSS16. 0 statistical software. Results In the 691 patients,there were 106 cases of Uyghur and 585 cases of Han; single polyps accounted for 43. 42%,while multiple polyps accounted for 56. 58%; accounting for 65. 70%of tubular adenomas,villous tubular adenomas accounting for 5. 21% and hyperplastic polyps accounted for 7.09%,the inflammatory polyps accounted for 23. 30%; sigmoid colonic polyps accounted for 45. 15%,descending colonic polyps accounted for 38. 35%,transverse colonic polyps accounted for 31. 26%,ascending colonic polyps accounted for 22. 29%; in the Uyghur group age of onset was earlier than that in the Han group,which the difference was statistically significant（ P 〈0. 01）. In the Uyghur group,HDL-C was lower than that in the Han group,which the difference was statistically significant（ P〈 0. 05）. There were no significant differences in gender,blood pressure,history of alcohol consumption,smoking history,clinical symptoms,polyps distribution site,the recurrence of polyps,past history,potassium,sodium,calcium,fasting blood glucose,TG,TC,LDL-C and etc. between the two groups（ P 〉0. 05）. Conclusion（ 1） The age of onset in Uyghur patients with colonic polyps was earlier than that in Han patients with the colonic polyps.（ 2） The HDL-C levels in Uyghur patients with colonic polyps was below than that in the Han patients with colonic polyps.（ 3） Multiple polyps was more common in the Han elderly patients with colonic polyps.