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抗磷脂综合征血栓形成机制的研究进展 被引量:13

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摘要 抗磷脂综合征(APS)是一种以持续存在抗磷脂抗体(aPL)为特征,以动静脉血栓形成和病态妊娠为主要临床表现的自身免疫性疾病.aPL是一群异质性自身抗体的总称,2006年的国际APS共识确定有诊断价值的aPL包括狼疮抗凝物(LA)、抗心磷脂抗体(aCL)和抗β2-糖蛋白Ⅰ抗体(anti-β2GP Ⅰ)[1].血栓是APS最重要的病理特征,但是aPL诱导血栓发生的机制仍不十分明确.
作者 黄媛 崔巍
出处 《中华医学杂志》 CAS CSCD 北大核心 2016年第39期3186-3189,共4页 National Medical Journal of China
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