期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

环指蛋白213基因与烟雾病及颅内大动脉狭窄/闭塞相关性研究进展

原文传递
导出
摘要 颅内大动脉狭窄/闭塞（intracranial major artery stenosis/occlusion,ICASO）是全世界范围内缺血性卒中常见的原因之一[1].无创性头颅血管评估技术的进步和普及,促使ICASO成为研究的热点,特别是危险因素及易感基因方面.烟雾病是一种少见的特殊的脑血管病,研究显示,两者在人种分布及血管受累的分布上具有一致性,因此有假说认为烟雾病是颅内大动脉狭窄/闭塞在亚裔人种高发的混杂因素,但临床医生有时很难以目前的检查手段来准确鉴别ICASO是来源于烟雾病还是与传统的动脉粥样硬化危险因素相关.
作者 成蔚阳 薛素芳 宋晓微 武剑
机构地区 首都医科大学宣武医院神经内科 北京清华长庚医院、清华大学医学中心、北京市脑重大疾病研究院脑卒中研究所
出处 《中华医学杂志》 CAS CSCD 北大核心 2016年第39期3197-3200,共4页 National Medical Journal of China
基金 国家自然科学基金（81371291、81400947） 北京市医管局人才培养计划登峰项目（DFL20152201） 北京市215卫生高层次人才学术带头人 清华大学自主科研计划（20161080076）
关键词 动脉狭窄 烟雾病 闭塞 颅内 13基因 相关性 蛋白2 环指
分类号 R743.3 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献37

  • 1Gorelick PB,Wong KS,Bae HJ,et al. Large artery intracranialocclusive disease : a large worldwide burden but a relativelyneglected frontier[ J ]. Stroke,2008,39 (8 ) ; 2396-2399. DOI :10.1161/STROKEAHA. 107. 505776.
  • 2Kamada F, Aoki Y, Narisawa A, et al. A genome-wideassociation study identifies RNF213 as the first Moyamoya diseasegene[J]. J Hum Genet, 2011,56 (1 ) : 34-40. DOI; 10. 1038/jhg. 2010.132.
  • 3Bang OY,Ryoo S, Kim SJ, et al. Adult Moyamoya Disease: ABurden of Intracranial Stenosis in East Asians [ J ]. PLoS One,2015,10(6) :e0130663. DOI: 10.1371/joumal. pone. 0130663.
  • 4Liu W, Morito D,Takashima S, et al. Identification of RNF213as a susceptibility gene for moyamoya disease and its possible rolein vascular development [J]. PLoS One,2011, 6(7): e22542.DOI :10.1371/joumal. pone. 0022542.
  • 5Deshaies RJ,Joazeiro CA. RING domain E3 ubiquitin ligases[J]. Annu Rev Biochem, 2009,78:399434. DOI: 10. 1146/annurev. biochem. 78.101807.093809.
  • 6Lupas AN, Martin J. AAA proteins[J]. Curr Opin Struct Biol,2002,12(6) :746-753.
  • 7Koizumi A, Kobayashi H, Liu W, et al. P. R4810K,apolymorphism of RNF213 , the susceptibility gene for moyamoyadisease,is associated with blood pressure [ J ]. Environ HealthPrev Med, 2013, 18 ?2) : 121-129. DOI: 10. 1007/sl2199-012-0299-1.
  • 8Zhou JB,Zhang T,Wang BF,et al. Identification of a novel genefusion HNF213-SLC26A11 in chronic myeloid leukemia by RNA-Seq[J]. Mol Med Rep,2013,7 (2) :591-597. DOI: 10. 3892/mmr. 2012. 1183. 2013,7 (2) : 591-597. DOI: 10. 3892/mmr.2012.1183.
  • 9Achrol AS,Guzman R,Lee M,et al. Pathophysiology andgenetic factors in moyamoya disease [ J ]. Neurosurg Focus, 2009,26(4) :E4. DOI: 10. 3171/2009.1. FOCUS08302.
  • 10Suzuki J,Takaku A. Cerebrovascular “moyamoya” disease.Disease showing abnormal net-like vessels in base of brain [ J ].Arch Neurol, 1969, 20(3) ;288-299.

二级参考文献18

  • 1各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量：33020
  • 2Della-Morte D,Guadagni F,Palmirotta R,et al.Genetics of ischemic stroke,stroke-related risk factors,stroke precursors and treatments[J].Pharmacogenomics,2012,13:595-613.
  • 3Meschia JF,Worrall BB,Rich SS.Genetic susceptibility to ischemic stroke[J].Nat Rev Neurol,2011,7:369-378.
  • 4Bevan S,Traylor M,Adib-Samii P,et al.Genetic heritability of ischemic stroke and the contribution of previously reported candidate gene and genomewide associations[J].Stroke,2012,43:3161-3167.
  • 5Caplan LR,Gorelick PB,Hier DB.Race,sex and occlusive cerebrovascular disease:a review[J].Stroke,1986,17:648-655.
  • 6Feldmann E,Daneault N,Kwan E,et al.Chinese-white differences in the distribution of occlusive cerebrovascular disease[J].Neurology,1990,40:1541-1545.
  • 7Kuriyama S,Kusaka Y,Fujimura M,et al.Prevalence and clinicoepidemiological features of moyamoya disease in Japan:findings from a nationwide epidemiological survey[J].Stroke,2008,39:42-47.
  • 8Kamada F,Aoki Y,Narisawa A,et al.A genome-wide association study identifies RNF213 as the first Moyamoya disease gene[J].J Hum Genet,2011,56:34-40.
  • 9Liu W,Morito D,Takashima S,et al.Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development[J].PLo S One,2011,6:e22542.
  • 10Wu Z,Jiang H,Zhang L,et al.Molecular analysis of RNF213 gene for moyamoya disease in the Chinese Han population[J].PLo S One,2012,7:e48179.

共引文献1

中华医学杂志
2016年 第39期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部