大理州吸毒人群HIV、HCV感染及相关高危因素调查研究

Investigation on the Infection of HIV, HCV and Association High Risk Factors among Drug Users

目的:了解大理州吸毒人群HIV、HCV感染情况及评估相关的高危因素,为更大范围内更有效地推广和完善吸毒哨点监测工作提供科学依据。方法:采集2015年1月至2015年6月大理州戒毒所新入所的423名吸毒人员的血样,检测HIV和HCV的感染情况,结合问卷调查资料,运用统计学方法分析与感染相关的危险因素。结果:在423名吸毒人员中HIV感染率为19.4%(82/423),HCV感染率为46.3%(196/423),在82例HIV感染者中,有96.3%(79/82)感染了HCV。多因素分析结果表明,注射吸毒年限、有注射吸毒史、共用针具不仅是HIV感染的高危因素,也是HCV感染的高危因素;此外,HCV感染还与年龄、每天注射吸毒次数正相关。结论:大理州吸毒人员中由于存在各种高危行为,使得吸毒人群HIV,HCV感染的比例较高,加速了HIV,HCV在该人群中的流行。

Objective： To understand the prevalence of HIV, HCV and estimate high risk factors among drug users in Dali Prefecture,thereby to provide the scientific basis for promoting and perfecting the prevention work more accurately in a larger range. Methods：The blood samples of 423 new drug users in Dali Detoxification Center from January 2015 to June 2015 were collected to detect the infection status of HIV and HCV. Using the data in questionnaire survey and statistical methods, risk factors related to infection were analyzed. Results： The infection rates among total 423 drug users were 19.4%（82/423）for HIV, 46.3%（196/423）for HCV. It is found that 96.3%（79/82）of the 82 HIV positive had infected with HCV. Multiple factor analysis indicated that the prevalence of HIV and HCV among drug users were positively related to drug using time, injection drug use, sharing needles. In addition, HCV infection was associated positively with the age of drug users and the times and quantity of drug addicts using per day. Conclusion： All sorts of high risk behavior associated with HIV and HCV infection result in the high HIV and HCV prevalence among drug users in Dali, which accelerate the HIV and HCV prevalence among this group of people.