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阻塞性睡眠呼吸暂停低通气综合征的治疗研究进展 被引量:39

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摘要 阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)是临床常见的睡眠呼吸疾病,以睡眠中间断通气量减低和呼吸暂停,伴或不伴打鼾为主要特征,这种间断呼吸暂停或通气量减低造成睡眠过程中反复发生的与缺血/再灌注损伤机制相似的间歇性低氧,引发全身氧化应激反应、炎性反应及交感神经兴奋性持续增强,导致多系统、多器官损伤,出现诸多并发症,如高血压、心脑血管病、肺动脉高压及肺心病、胰岛素抵抗及2型糖尿病、胃食管反流、性功能障碍、肾脏损伤、认知障碍等.
出处 《重庆医学》 CAS 北大核心 2016年第30期4300-4303,共4页 Chongqing medicine
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  • 1中华医学会呼吸病学分会睡眠呼吸障碍学组.阻塞性睡眠呼吸暂停低通气综合征诊治指南(2011年修订版)[J].中华结核和呼吸杂志,35:9-12.
  • 2McNicholas WT. Chronic obstructive pulmonary disease and obstructive sleep apnea: overlaps in pathophysiology, systemic inflammation, and cardiovascular disease [ J ]. Am J Respir Crit Care Med,2009,180 : 692-700.
  • 3Karadag F, Kirdar S, Karul AB, et al. The value of C-reactive protein as a marker of systemic inflammation in stable chronic obstructive pulmonary disease [ J ]. Eur J Intern Med, 2008,19 : 104-108.
  • 4Minoguchi K, Tazaki T, Yokoe T, et al. Elevated production of tumor necrosis factor-α by monoeytes in patients with obstructive sleep apnea syndrome[ J]. Chest,2004,126 : 1473-1479.
  • 5Barcelo A,de la Pena M, Ayllan O, et al. Increased plasma levels of asymmetric dimethylarginine and soluble CD40 ligand in patients with sleep apnea[ J]. Respiration ,2009,77 : 85-90.
  • 6Abbasi F, Asagmi T, Cooke JP, et al. Plasma concentrations of asymmetric dimetbylarginine are increased in patients with type 2 diabetes mellitus[ J]. Am J Cardiol,2001,88: 1201-1203.
  • 7Nural S, Gtinay E, Halici B, et al. Inflammatory processes and effects of continuous positive airway pressure (CPAP) in overlap syndrome[ J]. Inflammation ,2013,36 : 66-74.
  • 8Yokoe T, Minoguchi K, Matsuo H, et al. Elevated levels of C- reactive protein and inyerleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure[ J]. Circulation ,2003,107 : 1129-1134.
  • 9文富强,贺蓓.慢性阻塞性肺疾病全球创议(2011年修订版)解读[J].中华医学杂志,2012,92(14):939-940. 被引量:39
  • 10陈宝元,何权瀛.阻塞性睡眠呼吸暂停综合征的系统性损害[J].中华医学杂志,2012,92(18):1225-1227. 被引量:96

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