利用医院集中监测药物不良反应管理系统适时监测药物性肝损害

Timely Monitoring of Drug-induced Liver Injury by Using the Hospital Centralized Management System for Monitoring AD

目的探讨针对药物性肝损害患者采用医院集中监测药物不良反应管理系统加以适时监测后获得的效果。方法选择该院2014年8月—2016年8月表现出ALT(丙氨酸氨基转移酶)水平异常、或者AST(门冬氨酸氨基转移酶)水平异常、或者Tbil(总胆红素)水平异常的患者102例作为该次实验观察对象;针对患者用药过程中表现出药物性肝损害,有效利用医院集中监测药物不良反应管理系统加以适时监测,最终对监测结果进行分析。结果分析表现出药物不良反应的患者共包括15例,涉及到的药物种类共包括5类,共包括20种;临床属于不合理用药的患者共包括5例,涉及到的药物种类共包括7种。结论采用医院集中监测药物不良反应管理系统对患者用药情况加以适时监测,针对药物性肝损害信息可以进行有效明确,针对医院药物不良反应监测的集中开展提供有力依据。

Objective To study the effect of timely monitoring of patients with drug-induced liver injury by using the？hospital centralized management system for monitoring AD.Methods 102 cases of patients with abnormal ALT level,AST level and Tbil level in our hospital from August 2014 to August 2016 were selected as the observation objects,the drug-induced liver injury of patients in the medication course was given the timely monitoring by effective use of the hospital centralized management system for monitoring AD,and the monitoring results were analyzed finally.Results 15 cases were with drug adverse reactions,involving 5 categories,and there were 20 kinds in the 5 categories;5 cases were with clinical irrational medication in clinic,involving 7 categories of drugs.Conclusion The timely monitoring of medication of patients by using the hospital centralized management system for monitoring AD can effectively definite the drug-induced liver injury information and provide powerful basis for the concentrated development of hospital drug adverse reaction monitoring.