肝功能异常患者血清自身抗体的检测分析

Analysis of Test of Serum Autoantibodies in Patients with Abnormal Liver Function

目的探讨肝功能异常患者血清自身抗体的检测方法和结果。方法该次医学研究选择该院门诊2014年1月—2016年1月之间收治的178例肝功能异常患者以及82例不明原因肝功能异常患者为观察对象,同时,选择60例健康体检者作为对照组,全部患者均接受血清自身抗体检测,回顾分析患者的临床检测方法和结果。结果对照组、PBC组与AIH组观察对象的AST和ALT检测结果对比具有明显的统计学差异(P<0.05)。不同AIH亚型自身抗检测结果对比具有明显的统计学差异(P<0.05)。各组观察对象自身抗体检测结果对比具有明显的统计学差异(P<0.05)。结论对肝功能异常患者实施血清自身抗体检测,有助于患者疾病的准确诊断,并为其后续的治疗提供可靠依据。

Objective To study the method and result of test of serum autoantibodies in patients with abnormal liver function.Methods 178 cases of patients with abnormal liver function and 82 cases of patients with abnormal liver function for unknown reasons admitted and treated in clinic in our hospital from January 2014 to January 2016 were selected as the observation objects,at the same time,60 cases of healthy persons were selected as the control group,and all patients received the serum autoantibodies test,and the clinical test method and result of patients were retrospectively analyzed.Results There were obvious statistical differences in the AST and ALT test results between the control group,PBC group and AIH group（P〈0.05）,and there were obvious statistical differences in the AIH subtype autoantibodies test results（P〈0.05）,and there were obvious statistical differences in the autoantibodies test results between groups（P〈0.05）.Conclusion The implementation of serum autoantibodies test for patients with abnormal liver function contributes to the accurate diagnosis of patient＇s disease and providing reliable basis for the following treatment.