摘要
喹唑啉类化合物具有良好生物活性,在农药和医药等领域有着广泛的应用,如杀菌、杀虫、抗炎、抗病毒、抗高血压、抗结核、抗疟、抗肿瘤等,其分子设计、合成及生物活性研究目前仍是药物化学的一个研究热点,本文对近些年喹唑啉酮及其衍生物的合成情况进行了综述,并对未来的发展进行了展望。
Quinazoline compounds having good biological activity and have a wide range of applications In the field of pesticides and medicine, such as sterilization, insecticide, anti-inflammatory, anti-viral, anti-hypertensive, anti-tuberculosis, anti-malarial and anti-tumor, their molecular design, synthesis and biological activity is still a hot topic of medicinal chemistry. In this paper, quinazolinone derivatives and their synthesis were reviewed in re- cent years, and the development in the future.
出处
《化学工程师》
CAS
2016年第10期48-50,53,共4页
Chemical Engineer
关键词
喹唑啉酮
衍生物
催化合成
进展
quinazolinone
derivatives
catalytic synthesis
progress