54例重度ABO新生儿溶血病换血治疗结果分析

Analysis the Treatment Results of 54 Cases With Severe ABO Hemolytic Disease of Newborn by Blood Exchange Transfusion

目的探讨重度ABO新生儿溶血病换血治疗的效果,为临床治疗提供参考与指导。方法选择我院于2013年2月-2015年4月收治的重度ABO新生儿溶血病54例为研究对象。所有患儿在入院时,均实施总胆红素、直接胆红素、间接胆红素检测;患儿在应用换血治疗后,仍然实施3项指标的检测,对比前后变化情况。结果患儿经过治疗后,总胆红素和间接胆红素低于治疗前,比较差异具有统计学意义（P〈0.05）。结论针对重度ABO新生儿溶血病,实施换血治疗后,可取得良好疗效,延长患儿的生命,提高生存质量。

Objective For severe ABO hemolytic disease of the newborn,to discuss the effect of exchange transfusion therapy,to provide reference and guidance for the future of clinical treatment. Methods Chose 54 cases with severe ABO hemolytic disease of newborns in our hospital,from February 2013 to April 2015. All patients on admission,were to implement total bilirubin,direct bilirubin,indirect bilirubin measurements. After the application of exchange transfusion therapy, still implemented the detection of the 3 indicators, the changes before and after treatment were compared. Results In children after treatment,total bilirubin and indirect bilirubin was significantly lower than before treatment,the difference was statistically significant（P〈0.05）. Conclusion For severe ABO hemolytic disease of the newborn,the implementation of exchange transfusion therapy,can achieve a significant effect,prolong the lives of children and improve the quality of life.