甲泼尼龙联合阿奇霉素对小儿难治性支原体肺炎的治疗效果观察

Observation on the Curative Effect of Methylprednisolone Combined With Azithromycin in Children With Refractory Mycoplasma Pneumonia

目的探讨甲泼尼龙联合阿奇霉素治疗难治性支原体肺炎的临床效果。方法 58例小儿难治性支原体肺炎患儿随机分为对照组和观察组,两组患儿均给予对症支持治疗。29例对照组患儿给予阿奇霉素静脉滴注,29例观察组患儿在此基础上给予甲泼尼龙。结果对照组和观察组体温恢复时间分别为(12.4±2.3)d、(7.1±1.6)d,住院时间分别为(13.5±2.3)d、(8.8±1.4)d,治疗有效率分别为72.4%和93.1%,组间差异有统计学意义(P<0.05)。结论甲泼尼龙联合阿奇霉素治疗小儿难治性支原体肺炎效果好。

Objective To investigate the clinical effect of methylprednisolone combined with azithromycin in the treatment of refractory Mycoplasma pneumonia. Methods 58 cases of children with refractory Mycoplasma pneumonia were randomly divided into control group and observation group,two groups of children were given symptomatic support therapy. 29 cases of control group were given intravenous infusion of azithromycin,29 cases of infants in the observation group were given methylprednisolone. Results In control group and observation group,the body temperature recovery time was（12.4± 2.3）d,（7.1±1.6） d,the length of hospital stay was（13.5±2.3）d,（8.8 ±1.4）d,the treatment efficiency was 72.4% and 93.1% respectively,had significant difference between groups（P〈0.05）. Conclusion Methylprednisolone combined with azithromycin in treatment of children with refractory Mycoplasma pneumonia has a significant effect.