帕利哌酮与利培酮治疗精神分裂症的临床疗效比较及对社会功能的影响

Comparison of Clinical Efficacy of Paliperidone and Risperidone in the Treatment of Schizophrenia and Its Effect on Social Function

目的分析精神分裂症患者应用帕利哌酮与利培酮治疗的效果。方法随机选择在本院接受治疗的精神分裂症患者30例参与研究,随机平均分成两组,对照组选择利培酮治疗,观察组选择帕利哌酮治疗,比较两组效果。结果观察组治疗总有效率为93.33%,高于对照组总有效率73.33%;观察组治疗后物质生活态度、社会功能、躯体功能、心理功能得分均高于对照组(P<0.05)。结论帕利哌酮治疗精神分裂症能够提高疗效,改善社会功能,提高患者生活质量。

Objective To analyze the clinical efficacy of paliperidone and risperidone in the treatment of schizophrenia. Methods 30 patients with schizophrenia received treatment in our hospital were randomly divided into two groups randomly. The control group was treated with risperidone, the observation group was treated with paliperidone, and the effect of the two groups was compared.Results The total effective rate of the observation group was 93.33%,which was higher than that of the control group, the total effective rate was 73.33%. After treatment, the scores of life attitude, social function, physical function and psychological function of the observation group were all higher than those of the control group （P〈0.05）.Conclusion Paliperidone in treatment of schizophrenia can improve the curative effect, improve the social function, improve the quality of life of patients.