视网膜中央动脉阻塞的危险因素分析及相应防治措施的临床研究

Research on the risk factors of central retinal artery occlusion to analysis the corresponding clinical prevention therapeutic effect

目的分析导致视网膜中央动脉阻塞(CRVO)的危险因素,并考察相应防治措施的临床治疗效果。方法选取2014年3月至2015年3月来我院就诊的CRAO患者为主要研究对象,评估后选出86例受试者进行试验。试验前,对所有86例CRAO患者的基本病情进行调查,总结CRAO的病因、病理及相应的临床防治措施,通过视力检查、视野检查结果和视网膜电流图(ERG)检查结果评价相应防治措施(侵入性治疗、保守治疗)的临床治疗效果。结果 1 CRAO的发生与患者年龄及全身性疾病有密切关系,与性别无关。CRAO患者中伴随全身性疾病者占80.23%,主要以动脉粥样硬化、高血压、糖尿病等心血管疾病为主要原因,分别占到26.74%、20.93%、16.28%。另外,视网膜中央动脉(CRA)周围炎症也是引发CRAO的重要因素,占到10.47%;动脉痉挛、CRA外部压迫等也是CRAO发生的危险因素。2溶栓治疗前,两组患者的各种指标差异不具有统计学意义(P>0.05);溶栓治疗后,侵入性治疗组患者各项指标及视力恢复情况(总有效率高达84.78%)优于保守治疗组(总有效率为67.50%),说明侵入性治疗对CRAO疾病的预后和恢复情况优于保守治疗组,差异具有统计学意义(P<0.05)。结论中老年人心脑血管、血流动力学异常均是导致CRAO的重要因素,发病后应及时对其进行相应的保守治疗或侵入性治疗,最大程度上改善患者视力。

Objective To explore the risk factors of central retinal artery occlusion（ CRAO） to analysis the corre-sponding clinical prevention therapeutic effect.Methods Select 86 cases CRAO patients in our hospital from March 2014 to March 2015 as the main research object.Before the test, investigate the basic medical history of all the 86 cases CRAO patients, summarizes the etiology, pathology and clinical prevention measures; according to the visual acuity, visual field and electroretinogram （ERG） results to evaluat the corresponding clinical prevention therapeutic effect（invasive treatment, conservative treatment） .Results ①CRAO patients associated with systemic disease accounted for 80.23%, mainly in atherosclerosis, cardiovascular disease such as atherosclerosis, hypertension and diabetes, accounted for 26.74%, 20.93%and 26.74%respectively.In addition, inflammation around CRA is also an important factor causing CRAO, ac-counted for 10.47%.Arterial spasm, CRA external oppression is also risk factors for CRAO.②before the thrombolysis treatment, two groups of patients with no statistically significant difference（ P 〉0.05）;After thrombolysis treatment, vi-sion recovery of invasive treatment group（total effective rate up to 84.78%） is better than conservative treatment group（the total effective rate was 67.50%）, with statistically significant difference（ P 〈0.05）.Conclusion Heart cerebrovascular and hemodynamic abnormalities are important risk factors causing CRAO.Corresponding conservative therapy and interven-tional therapy must be given to improve CRAO patients＇eyesight.