胃癌患者主要照顾者的睡眠质量及其对生活质量的影响

Sleep quality and its impact on quality of life in the primary caregiver of patients with gastric cancer

目的本研究旨在调查胃癌患者主要照顾者的睡眠质量及其对生活质量的影响，为提高其睡眠质量、进而促进其身心健康提供依据。方法本研究采用方便抽样方法抽取190名胃癌患者主要照顾者为研究对象。研究使用匹兹堡睡眠质量量表（PSQI）和36条目简明量表（SF-36）分别对研究对象的睡眠和生活质量进行测定。采用t检验对本研究人群与普通人群的睡眠质量进行比较；采用Pearson相关分析和多元线性回归对睡眠质量和生活质量的关系进行评估。结果研究对象平均PSQI总分为（8．06±4．05）分，43．9％研究对象睡眠质量较差。与普通人群相比，除了催眠药物使用这一维度之外，本研究对象的其余6个维度得分以及总分均较高（P〈0．01）。PSQI总分与生活质量的身体疼痛这一维度呈低度正相关（r=0．15，P=0．04）。睡眠质量好者（PSQI〈8）较睡眠质量差者（PSQI≥8）具有较好的生理职能（t=2．30，P=0．02）和社会功能（t=2．12，P=0．04）。多元回归分析提示在控制了年龄和性别因素之后，睡眠质量仅对生活质量的身体疼痛这一维度产生影响（β=0．15，t=2．04，P=0．04）。结论胃癌患者主要照顾者睡眠质量较差，且睡眠质量会对其生活质量的个别维度（身体疼痛、生理职能和社会功能）产生影响。今后的临床实践中，应重视对于这方面的评估与干预。

Objective To investigate the sleep quality and its impact on quality of life in the primary caregivers of patients with gastric cancer, thereby providing guidance on the promotion of their sleep and psycho- physical function. Methods This was a convenient sampling study that enrolled 190 primary caregivers of patients with gastric cancer from two general hospitals in Xi＇an, China. The sleep quality, quality of life, and baseline data were evaluated using Pittsburgh sleep quality index （PSQI） , SF-36 health survey （SF-36）. t test was used to compare the sleep quality between the earegivers and the general population. Pearson correlation and multiple linear regression analysis were conducted to explore the relationship between sleep quality and quality of life. Results The mean global PSQI score was （8.06 ±4.05） ; 43.9% of them had poor sleep （PSQI≥8）. Compared to the general population, the global PSQI score and the scores of the six factors were higher （P 〈 0.01 ） in this sample, indicating a poorer sleep quality, except for the factor of ＂use of sleep medication＂. The global PSQI score was positively correlated with the score of BP （ r = 0. 15, P = 0. 04 ）. Compared with participants who had a good sleep （ PSQI 〈 8）, those with a poor sleep score were lower on RP （ t = 2. 30, P = 0.02） and SF （t = 2. 12, P = O. 04）. Multiple linear regression analysis indicated that sleep quality was only a factor of BP （β =0. 15, t =2. 04, P =0.04） rather than RP and SF, after controlling for age and gender. Conclusions The primary caregivers of patients with gastric cancer have poorer sleep quality, compared to the general population. Sleep quality is related to some dimensions of quality of life, such as BP, RP, and SF. Health care providers should pay attention to the sleep and quality of life of the caregivers, and deliver corresponding interventions if necessary.